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Fats can accumulate in the brain and cause depression.

Scientists have long observed a clear relationship between obesity and depression. It may seem that they are interconnected only by human complexes about their excess weight, but no – a new study proved that complex biological processes are also involved in this matter. For example, researchers at the University of Glasgow have found that depression symptoms sometimes occur when human dietary fats accumulate in a specific area of ​​the brain. In 2018, a study was conducted in which mice were given high fat foods. Subsequently, these individuals began to show symptoms of depression until antibiotics returned the state of the microflora to normal. The researchers then concluded that a high-fat diet could cultivate certain groups of intestinal bacteria that cause depression causing neurochemical changes. New research has moved away from the study of intestinal bacteria, and revealed the processes that occur in the human brain. At the very beginning of Continue Reading

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How does scorpion poison detect brain cancer?

Glioma is considered the most dangerous type of brain tumor. Not only does it react poorly to conventional chemotherapy, it also hides well from scanners, spreading across a wide range of brain tissue. It seems that in the near future the treatment of this type of cancer will become a little easier – scientists have created a new type of tumor imaging, which causes cancer cells to "glow like a Christmas tree." The most interesting thing is that based on the technology lies an amino acid contained in the scorpion venom. To make the tumor more noticeable and highlight its facets for subsequent removal, researchers from Cedars-Sinai Medical Center used a compound called tosulehistid (BLZ-100). It is a synthetic variation of a peptide extracted from scorpion venom that easily binds to cancer cells in the brain. By adding a fluorescent dye to it, the researchers made it well visible with Continue Reading

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Modified viruses prevent death from infectious disease

Many species of life-threatening bacteria are immune to antibiotics, and because of this, about 700,000 people die each year. Of course, researchers from all over the world are trying to develop new drugs, but the process has been going on for quite a while, while they have another, less proven method of treating infections – the use of viruses that eat bacteria. Recently, an experimental and extremely risky method helped save the life of a girl, whose probability of survival was less than one percent. How was the treatment? The girl who escaped imminent death was seventeen Isabelle Carnell Holdey. Even as a child, she suffered from chronic infection with Mycobacterium abscessus and from cystic fibrosis, a hereditary disease accompanied by damage to the endocrine glands and dysfunction of respiration. She underwent a lung transplantation, after which her condition worsened greatly: the infection was activated with double force, the liver Continue Reading

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Google has advocated the use of CRISPR to prevent heart disease

Have you ever wondered why some lucky people eat chips, do not play sports and, nevertheless, do not clog arteries? Perhaps this is due to the fact that they have happy genes. And here, Alphabet (the parent company of Google) is funding a start-up company that plans to use gene editing to distribute successful DNA variants using the CRISPR tool. You should already know what CRISPR is. Cardiologists involved in this movement say that DNA injection injections can "provide lifelong protection against heart disease." Google supports CRISPR Startup Verve Therapeutics raised $ 58.5 million from sponsors including Google Ventures. What makes Verve different? Most gene therapy companies are focused on rare diseases like hemophilia. But Verve believes that editing people's DNA will help eliminate the most common cause of death. Scientists know that some people have very low cholesterol levels, no matter how hard they try. They even have a Continue Reading

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# video | Created "breathing" analogue of the human lung

Scientists from Rice University used 3D printing technology to create a miniature analogue of the human lung. The artificial organ turned out to be quite tiny – no more than a coin, but as the Popular Mechanics portal notes, in the future this revolutionary model can have a serious impact on the development of transplantology and moving away from the shortage of organs needed for transplantation. Only in the United States alone, 114,000 people are waiting for their turn for the transplantation of certain organs. In addition, during organ transplantation, people have to take special medications that block the body's rejection of new transplanted organs. According to scientists, bio-printed organs will be able to solve both problems. “One of the main obstacles to creating an analogue of a functioning living tissue was the inability to print complex vascular systems, which in the body serve to transport blood, air, lymph and Continue Reading

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Wearable on the face "laboratory" allows you to replace a blood test

Engineers at the Fluid Interfaces Group at the Massachusetts Institute of Technology (MIT) created a wearable sensor that attaches to a person’s cheek and collects information about the concentration of certain biological markers in saliva in real time. The developers of the device on the MIT website note that such a device can save a person from the need for blood tests. It is equipped with a compact biomechanical paper sensor that responds to substances of interest in saliva, allowing you to monitor the state of the body. A blood test is a fairly reliable way to find out what is happening and in what condition is the human body as a whole and its individual organs in particular. However, a blood test is not always convenient, it is difficult to carry out constantly, despite the fact that some studies require monitoring changes in the concentration of certain substances in Continue Reading

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Neurocomputer interfaces will give people extra power

Once, on a rainy morning, Bill was driving his motorcycle, when suddenly a mail truck stopped in front of him. Bill did not have time. The accident paralyzed his lower body. His autonomy – what was left of her – was reduced to voice commands, which allowed him to raise and lower the blinds in the room or adjust the angle of the bed with a motor. Otherwise, he relies on round-the-clock assistance. Vanya does not know Ann, who has Parkinson's disease; her hands tremble when she tries to apply makeup or weed the garden. None of them knows Steve, who became blind in adulthood due to a degenerative disease and whom his sister helps to navigate the world. Presenting the three of them together sounds like the beginning of a bad joke: a blind, paralyzed, and parkinson guy somehow enter the bar. But their stories are combined in a Continue Reading

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Оправданы ли риски использования CRISPR? Давайте поразмыслим

Новые заголовки на тему CRISPR появляются каждую неделю, рекламируя потенциал редактирования генов переделать известный нам мир — от создания более подходящих источников пищи до спасения коралловых рифов и улучшения методов лечения рака. Однако бывают и не очень приятные новости: к примеру, есть возможность непреднамеренно повредить ДНК во время редактирования или отредактировать нецелевые участки. Кроме того, учитывая всю сложность механизма ДНК, мы даже и близко не готовы испытывать CRISPR на людях. Официально, во всяком случае — «по-черному» прецеденты уже появляются. Возможности очень большие, и никакое из последствий CRISPR не имеет мгновенного эффекта, хорошего или плохого. Впрочем, область еще в зачаточном состоянии, и при наличии должного объема исследований мы получаем прекрасный потенциал изменить жизнь, сделать ее лучше. Насколько опасен CRISPR? Без исследований — очень И все же, на мой взгляд, мы сталкиваемся с более серьезным препятствием, чем потенциальные недостатки технологии CRISPR. Несмотря на потенциал этого инструмента решить ряд крупнейших мировых проблем, на Continue Reading

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Open heart surgery in the middle of the street – is it possible?

Open surgery is an extremely difficult task, requiring the most sterile conditions and the maximum concentration of surgeons. Unfortunately, sometimes these conditions cannot be fully met, as people can simply die on the way to the hospital and it is better to perform the operation on the spot. In this situation, recently doctors from the English city of Durham found themselves – a man was stabbed by a knife, which required immediate open-heart surgery. Did the surgeons manage to do this? A rescue team led by surgeon Chris Smith got to the scene in just 15 minutes, all thanks to a well-developed infrastructure and the availability of helicopters. The surgeon was afraid that the man would not stand the flight to the hospital, so he decided to perform a heart operation right in the middle of the street. In such conditions, to guarantee sterility and maximum concentration, of course, was Continue Reading

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CRISPR injection into the brain of the embryo can cure genetic disorder

A rather controversial new study suggests that there may be a way to prevent Angelman syndrome, a genetic disorder that can cause seizures, difficulties in communication, and is associated with autistic spectrum diseases. The fact is that in order to test the experimental treatment in mice, scientists had to inject CRISPR enzymes, which edit the gene, directly into the brain of the developing fetus. Genetically modified fruits are uncharted ethical territory. Potentially beneficial experimental treatment should be balanced by anxiety about the patient's well-being. As always, on mice The treatment, which was presented at a scientific conference in February, but has not yet been included in academic journals, affects a specific UBE3A gene that helps cells break down and process proteins. When this gene mutates in the developing brain, Angelman syndrome occurs. But research shows that it can be avoided if the genes turn on before birth. In an experiment Continue Reading