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Fats can accumulate in the brain and cause depression.

Scientists have long observed a clear relationship between obesity and depression. It may seem that they are interconnected only by human complexes about their excess weight, but no – a new study proved that complex biological processes are also involved in this matter. For example, researchers at the University of Glasgow have found that depression symptoms sometimes occur when human dietary fats accumulate in a specific area of ​​the brain. In 2018, a study was conducted in which mice were given high fat foods. Subsequently, these individuals began to show symptoms of depression until antibiotics returned the state of the microflora to normal. The researchers then concluded that a high-fat diet could cultivate certain groups of intestinal bacteria that cause depression causing neurochemical changes. New research has moved away from the study of intestinal bacteria, and revealed the processes that occur in the human brain. At the very beginning of Continue Reading

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How does scorpion poison detect brain cancer?

Glioma is considered the most dangerous type of brain tumor. Not only does it react poorly to conventional chemotherapy, it also hides well from scanners, spreading across a wide range of brain tissue. It seems that in the near future the treatment of this type of cancer will become a little easier – scientists have created a new type of tumor imaging, which causes cancer cells to "glow like a Christmas tree." The most interesting thing is that based on the technology lies an amino acid contained in the scorpion venom. To make the tumor more noticeable and highlight its facets for subsequent removal, researchers from Cedars-Sinai Medical Center used a compound called tosulehistid (BLZ-100). It is a synthetic variation of a peptide extracted from scorpion venom that easily binds to cancer cells in the brain. By adding a fluorescent dye to it, the researchers made it well visible with Continue Reading

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CRISPR injection into the brain of the embryo can cure genetic disorder

A rather controversial new study suggests that there may be a way to prevent Angelman syndrome, a genetic disorder that can cause seizures, difficulties in communication, and is associated with autistic spectrum diseases. The fact is that in order to test the experimental treatment in mice, scientists had to inject CRISPR enzymes, which edit the gene, directly into the brain of the developing fetus. Genetically modified fruits are uncharted ethical territory. Potentially beneficial experimental treatment should be balanced by anxiety about the patient's well-being. As always, on mice The treatment, which was presented at a scientific conference in February, but has not yet been included in academic journals, affects a specific UBE3A gene that helps cells break down and process proteins. When this gene mutates in the developing brain, Angelman syndrome occurs. But research shows that it can be avoided if the genes turn on before birth. In an experiment Continue Reading

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Electrical brain stimulation temporarily rejuvenates the human brain for 50 years

Electrical brain stimulation can alleviate the symptoms of depression, bring patients out of a vegetative state, and even reduce the effects of Parkinson's disease. Recently, a group of scientists from the University of Boston demonstrated a technique that is able to restore the working memory of 70-year-old people so that it starts working like that of 20-year-old young people. It is noteworthy that the technique does not require implantation of electrodes directly into the patient's brain – stimulation is carried out through the scalp. The group was determined to improve the working memory of older people from the very beginning, and acted under the guidance of neurobiologist Rob Reinhart. Special attention was paid to working memorywhich allows you to memorize the information that is needed when performing a particular task. For example, it turns on when a person recalls a list of products to buy, looks for car keys, or Continue Reading

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Scientists have created a transparent implant for the study of the living brain in real time

Scientists from the University of Minnesota have created a unique See-Shells implant for the skull, which will help unravel the causes of Alzheimer's and Parkinson's diseases and, equally important, find these treatments, as well as other dangerous diseases. The implant is a solid transparent shell created using 3D printing technology. According to the creators of the implant, such a device helps to look into the head and see how diseases or injuries affect the entire organ as a whole. A detailed article on the development and research of scientists was published magazine Nature Communications. “The new device allows us to visualize brain activity and interact with a large amount of surface areas, in this case, the whole cerebral cortex,” explains one of the authors of the design, Suhasa Kodandaramayah. Previously, experts could only observe certain areas of the brain in order to study them in detail. The new tool, See-Shell, Continue Reading

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Electrical synchronization of brain areas can cure depression

Stimulation of the brain by electrical impulses is actively used to treat various mental illnesses. Most often, this requires surgical implantation of the electrodes, but the method called transcranial stimulation with alternating current (tACS) does not imply interference. Thanks to him, researchers have already managed to cure auditory hallucinations in schizophrenics and reduce the sensations of back pain in one of the patients. A new study of its kind has shown that technology can also cure deep depression. Unlike deep brain stimulation (Deep Brain Stimulation), tACS uses softer electrical impulses and synchronizes the activity of different areas of the brain. Researchers noted that in patients with deep depression, electrical oscillations of the left frontal area of ​​the brain occur much more actively than the right. To correct the so-called “frontal alpha asymmetry,” the researchers decided to balance the activity of both areas with the help of the very tACS-stimulation. The Continue Reading

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Cotton swabs almost led to inflammation of the brain tissue

Otolaryngologists have repeatedly advised not to use cotton swabs and other items to clean the ear canal, but many are still skeptical of this recommendation. So did one resident of England, until due to the abandoned cotton from the stick in his ear he developed an intracranial abscess. Details of the story tells the publication of Live Science. According to interviewed doctors at Coventry Hospital, the patient developed necrotizing external otitis media, which was caused by a foreign object in the ear canal. The man turned to the clinic with complaints of earache, convulsive seizures and hearing loss. After he had a CT scan, doctors saw two inflammations between the upper meninges (intracranial abscesses). As a result of checking the auditory canals, they found a piece of cotton swab to clean the ears. Necrotizing external otitis media usually develops because of the Pseudomonas aeruginosa, which gets into the ear canal Continue Reading