For the first time in history, laboratory-grown heart muscle cells transplanted into humans

Scientists from the Japanese University of Osaka reported successful and unique transplantation. They decided to treat the patient's heart, but instead of organ transplantation, they completely used laboratory-grown heart muscle cells. On the damaged areas of the human heart, they placed decomposable sheets (0.1 mm thick and 4-5 cm long), which contained cells of the heart muscle. They were grown from induced pluripotent stem cells. These are cells that are taken from various tissues, and then reprogrammed using genetic engineering methods. A patient who has a new heart muscle transplant suffers from ischemic cardiomyopathy. Usually this disease requires a complete organ transplant. But scientists hope that muscle cells will secrete a protein that will help restore blood vessels and improve heart function. Professor Yoshiki Sawa during a press conference. Photo: KYODO The patient's condition will be monitored over the next year. Over the next three years, they plan to repeat Continue Reading

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Google has advocated the use of CRISPR to prevent heart disease

Have you ever wondered why some lucky people eat chips, do not play sports and, nevertheless, do not clog arteries? Perhaps this is due to the fact that they have happy genes. And here, Alphabet (the parent company of Google) is funding a start-up company that plans to use gene editing to distribute successful DNA variants using the CRISPR tool. You should already know what CRISPR is. Cardiologists involved in this movement say that DNA injection injections can "provide lifelong protection against heart disease." Google supports CRISPR Startup Verve Therapeutics raised $ 58.5 million from sponsors including Google Ventures. What makes Verve different? Most gene therapy companies are focused on rare diseases like hemophilia. But Verve believes that editing people's DNA will help eliminate the most common cause of death. Scientists know that some people have very low cholesterol levels, no matter how hard they try. They even have a Continue Reading

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Open heart surgery in the middle of the street – is it possible?

Open surgery is an extremely difficult task, requiring the most sterile conditions and the maximum concentration of surgeons. Unfortunately, sometimes these conditions cannot be fully met, as people can simply die on the way to the hospital and it is better to perform the operation on the spot. In this situation, recently doctors from the English city of Durham found themselves – a man was stabbed by a knife, which required immediate open-heart surgery. Did the surgeons manage to do this? A rescue team led by surgeon Chris Smith got to the scene in just 15 minutes, all thanks to a well-developed infrastructure and the availability of helicopters. The surgeon was afraid that the man would not stand the flight to the hospital, so he decided to perform a heart operation right in the middle of the street. In such conditions, to guarantee sterility and maximum concentration, of course, was Continue Reading

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Scientists have created a self-managed robot surgeon for heart surgery

Specialists from the Boston Children's Hospital (USA) have developed and successfully conducted tests of a flexible autonomous robotic catheter that can independently touch the inside of the heart and reach the heart valves. Verification of the invention for autonomous detection of heart valves was carried out on the living hearts of pigs. About the advanced development of scientists reports article published in the journal Science Robotics. At present, surgeons perform operations in the cardiac cavity in two different ways: minimally invasive, when the sternum is not cut, and all actions are performed through a small puncture between the ribs, and by the transsternal method, when access to the heart is opened through the cut sternum. The latter case requires a longer recovery period and can sometimes be accompanied by complications. Minimally invasive operations, in turn, are performed using guided flexible catheters with minimal surgical intervention. The most difficult thing in Continue Reading


3D glasses have been adopted by Polish heart surgeons

Cardiologists turned to three-dimensional technology to improve the accuracy of operations, reports Reuters. They operated on the patient in special glasses that allow them to see what is happening in the patient's chest in three dimensions. Surgeons already know the systems that collect information about the human body during the operation, but they present the data in the form of two-dimensional images on a regular monitor. Such images do not give the required depth, and doctors are forced to constantly re-examine themselves, touching the tissues of the organ. The ability to see everything in a three-dimensional environment allows the surgeon to maneuver more freely during the operation. We are talking about the transmission of real-time information obtained during the ultrasound scan. These data are transmitted immediately to special glasses, which are a holographic display of mixed reality. It is known: the method was tested during the operation of one patient Continue Reading

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Presented the world's first heart, printed on a 3D printer made from human fabrics

Scientists from all over the world are trying to use 3D printing technology to create artificial organs. If they can prove their safety, effectiveness and durability, in the future, mankind will be able to forget about the donation, and introduce artificial analogues into the bodies of people who need healthy organs. Previously, researchers from Switzerland managed to create a mechanical copy of the human heart, but it was printed from silicone. Since silicone can be rejected by the body, scientists should have created a heart from the natural tissues of a person — this they finally managed to do. So, at least, scientists from Tel-Aviv University claim – they used only human tissues to print a small heart, which would not be rejected by the body. The structure of an artificial organ includes the vessels necessary for its work, collagen protein to create connective tissue and various biological molecules. This Continue Reading


How do 3D heart operations in Belarus

For a year, Belarusian heart surgeons have performed unique 3D heart surgeries. They help to cope with the insidious disease that leads to death. This week, experts from the leading clinic in Germany came to learn from the experience of such operations at the Republican Scientific and Practical Center Cardiology. "First – shortness of breath, dizziness, and in some cases death immediately occurs" Yuri Galenchik is 39 years old. A few days ago, he underwent 3D heart surgery due to hypertrophic cardiomyopathy. For the past year, such operations have been done in 3D. And today in Belarus there are already about 20 such operated patients. The difference between a 3D operation and a conventional one is that the heart surgeon can more precisely excise the hypertrophied muscle tissue of the heart. This is due to the fact that the doctor has an individual model of the organ and he understands Continue Reading


Space medicine will help Russians with heart failure

Specialists of the Institute of Biomedical Problems (IBMP) are planning to use space inventions in terrestrial medicine to help patients and old people in Russia with heart failure. One of these inventions is myostimulation. The electrodes are superimposed on the muscles, which are seriously affected in space flight conditions. The electric current causes them to contract and relax, so they are trained. “The technique tested in Earth orbit will help heart failure patients and old people. The Institute of Biomedical Problems (IMBP) of the Russian Academy of Sciences plans to use the muscle stimulation method used by the ISS crew on Earth. IMBP RAS conducts experiments on the introduction of miostimulation in the clinical practice of Russian medical institutions. According to the IBMP, the Institute, together with the University of Bern (Switzerland), received a grant from the Ministry of Education and Science to study the possibility of using space inventions Continue Reading

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How does poor sleep lead to heart disease and death?

According to the World Health Organization, cardiovascular diseases account for 31% of all deaths in the world. They develop with improper diet, smoking, lack of physical activity and improper sleep patterns. If scientists already know how food consumed, nicotine, and a sedentary lifestyle affect the heart and blood vessels, then the effect of an abnormal sleep pattern has not yet been studied. However, the mystery has already been solved – Harvard researchers have discovered an unexpected chemical reaction linking poor sleep with heart disease. In their study, the team decided to understand how inadequate sleep leads to the development of atherosclerosis, one of the most frequent cardiovascular diseases. In the course of this disease, fatty plaques form in the human arteries that interfere with free blood flow and lead to a decrease in the elasticity of the blood vessels and their inflammation. Subsequently, more serious problems arise, such as seizures Continue Reading

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Russia has created an artificial children's heart with a two-year service life

Heart transplantation saves thousands of lives, but waiting for a donor organ can last quite a long time. Artificial hearts that already exist in the USA, but are worth crazy money, help us to live to this point. Researchers from the Russian military plant Progress have mastered the production of miniature pumps, which, with their low cost, provide at least two years of life. Artificial hearts are designed for children, and are comparable in size to candy. Special conditions were required for assembling mechanisms as accurate as clocks. The workshop in which artificial hearts are assembled is separated from the plant foundation by dampers – devices that absorb any vibrations. Such conditions are necessary for maximum accuracy, because the pumps consist of parts the size of poppy seeds, which are interconnected under a microscope. In order not to scratch them, engineers use brass tools and wooden sticks – otherwise, blood Continue Reading